2. Metabolic Disease

Metabolic Disease

Metabolic Disease

Related Products

PDF 53.7 MB

Metabolic diseases is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus, and all cause mortality. Associated conditions include hyperuricemia, fatty liver (especially in concurrent obesity) progressing to nonalcoholic fatty liver disease, polycystic ovarian syndrome (in women), erectile dysfunction (in men), and acanthosis nigricans. Metabolic disease modeling is an essential component of biomedical research and a mandatory prerequisite for the treatment of human disease. Somatic genome editing using CRISPR/Cas9 might be used to establish novel metabolic disease models.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W016203
    Phenylpyruvic acid sodium 114-76-1 98.24%
    Phenylpyruvic acid sodium is a endogenous metabolite that participates in the synthesis of 3-phenyllactic acid (PLA) by lactate dehydrogenase. Phenylpyruvic acid is a precursor of the antifungal compound phenyllactic acid. Phenylpyruvic acid can improve the antifungal activity of eight lactic acid bacterial strains through the addition into a dedined growth medium. Phenylpyruvic acid demonstrates improved inhibitory activity against fungal bread contaminants Aspergillus niger and Penicillium roqueforti. Phenylpyruvic acid affects enzyme activity of the pentose phosphate pathway involved in the oxidative phase in rat brain homogenates. Phenylpyruvic acid can reduce glucose-6-phosphate dehydrogenase activity.
    Phenylpyruvic acid sodium
  • HY-W028263
    6-Hydroxyflavanone 4250-77-5 99.87%
    6-Hydroxyflavanone is a compound that can be isolated from the Muntingia calabura leaves. 6-Hydroxyflavanone targets cyclooxygenase-2 (COX-2), 5-lipoxygenase (5-LOX), and opioid and GABA-A receptors that has anti-inflammatory and anti-neuropathic pain potential. 6-Hydroxyflavanone can be used for the research of diabetes.
    6-Hydroxyflavanone
  • HY-W037819
    6-Methylpterin 708-75-8 99.84%
    6-Methylpterin is a derivative of the essential B vitamin Folic acid (HY-16637). 6-Methylpterin generates singlet oxygen and hydrogen peroxide when exposed to Photoirradiation. 6-Methylpterin can be used for the detection of pterins in urine.
    6-Methylpterin
  • HY-W131711
    Methyl dec-9-enoate 25601-41-6 98%
    Methyl dec-9-enoate, a fatty ester, is commonly used as a raw material for paints, inks and plastic additives.
    Methyl dec-9-enoate
  • HY-W140401
    Dimethyl nonanedioate 1732-10-1 98.77%
    Dimethyl nonanedioate (Nonanedioic acid dimethyl ester) is an ester product.
    Dimethyl nonanedioate
  • HY-W165608
    5-(3'-Hydroxyphenyl)-γ-valerolactone 21618-91-7 99.90%
    5-(3'-Hydroxyphenyl)-γ-valerolactone is a flavan-3-ols metabolitec of human faecal microbiota.
    5-(3'-Hydroxyphenyl)-γ-valerolactone
  • HY-W207195
    7-Hydroxy-4-phenylcoumarin 2555-30-8
    7-Hydroxy-4-phenylcoumarin is a dual ALDH-2 and MAO inhibitor, with IC50 values of 1.5 and 0.5 µM, respectively.
    7-Hydroxy-4-phenylcoumarin
  • HY-W269368
    Heptacosane 593-49-7 98.73%
    Heptacosane is an ester product.
    Heptacosane
  • HY-W440238
    22-Hydroxydocosanoic acid 506-45-6 ≥98.0%
    22-Hydroxydocosanoic acid (omega-Hydroxybehenic acid) is an ester product.
    22-Hydroxydocosanoic acid
  • HY-W509381
    4-Hydroxyindole-3-acetic acid 56395-08-5
    4-Hydroxyindole-3-acetic acid (4HIAA) is a metabolite of Psilocybin and Psilocin.
    4-Hydroxyindole-3-acetic acid
  • HY-W576312
    N,N-Dimethyltryptamine N-oxide 948-19-6 99.8%
    N,N-Dimethyltryptamine N-oxide is a metabolite of N,N-Dimethyltryptamine.
    N,N-Dimethyltryptamine N-oxide
  • HY-W585839
    Bis(2-chloroethyl) phosphate 3040-56-0 98%
    Bis (2-chloroethyl) phosphate (BCEP) is an organophosphate esters (OPEs) . Bis (2-chloroethyl) phosphate are positively correlated with an increased risk of sarcopenia.Bis (2-chloroethyl) phosphate has the nephrotoxic potential.
    Bis(2-chloroethyl) phosphate
  • HY-W590849
    F1874-108 335223-43-3 99.22%
    F1874-108 is an inhibitor of brassinosteroid biosynthesis and signal transduction.
    F1874-108
  • HY-W613967
    Hexacosanedioicacid 3365-67-1 99.93%
    Hexacosanedioicacid is an ester product.
    Hexacosanedioicacid
  • HY-W684071
    20α-Dihydrocortisol 1719-79-5
    20α-Dihydrocortisol (20α-DHF) is a metabolite of Hydrocortisone (Cortisol) (HY-N0583).
    20α-Dihydrocortisol
  • HY-W709961
    5-OAHSA 1997286-66-4 ≥99.0%
    5-OAHSA (1-(3-Carboxypropyl)tetradecyl (9Z)-9-octadecenoate) is a endogenous lipid. 5-OAHSA reduces the level of blood glucose, improves the glucose tolerance, and stimulates the the secretion of GLP-1 and insulin. 5-OAHSA exhibits potential in regulating metabolic and inflammatory responses.
    5-OAHSA
  • HY-W710928
    2-(2-Methylenecyclopropyl)acetic acid 1073-00-3
    2-(2-Methylenecyclopropyl)acetic acid is an ester product.
    2-(2-Methylenecyclopropyl)acetic acid
  • HY-W716889
    2,6,10,14-Tetramethylhexadecane 638-36-8 98.0%
    2,6,10,14-Tetramethylhexadecane is an ester product.
    2,6,10,14-Tetramethylhexadecane
  • HY-W718357
    10(E)-Nonadecenoic acid 147527-21-7 99.0%
    10(E)-Nonadecenoic acid is an isomer of 10Z-Nonadecenoic acid (HY-113450). 10(E)-Nonadecenoic acid is a long-chain fatty acid.
    10(E)-Nonadecenoic acid
  • HY-W753474
    1,2-Dipalmitelaidoyl-sn-glycero-3-phosphocholine 56816-00-3 99%
    1,2-Dipalmitelaidoyl-sn-glycero-3-phosphocholine (PC(16:1(9E)/16:1(9E))) is an ester product.
    1,2-Dipalmitelaidoyl-sn-glycero-3-phosphocholine
Cat. No. Product Name / Synonyms Application Reactivity